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Translational Medicine / 转化医学HIF-2, Renal Cell Carcinoma, Metabolism

M. Celeste Simon

PhD

🏢University of Pennsylvania🌐USA

Professor of Cell and Developmental Biology

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Key Contributions

👥Biography 个人简介

M. Celeste Simon has defined non-redundant roles for HIF-1 and HIF-2 in tumor biology, including pro-oncogenic actions of HIF-2 in VHL-deficient renal cell carcinoma. Her lab has illuminated hypoxic metabolic reprogramming and lipid droplet biology in cancer. She leads cancer cell biology research at Penn.

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🧪Research Fields 研究领域

HIF-2
clear cell RCC
tumor metabolism
hypoxia
VHL

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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