Silke Gillessen
西尔克·吉莱森
MD
Head, Genitourinary Oncology and Lead Investigator, Prostate Cancer Trials泌尿肿瘤科主任及前列腺癌试验首席研究员
👥Biography 个人简介
Prof. Silke Gillessen is a leading European prostate cancer specialist at IOSI Switzerland and co-chair of the Advanced Prostate Cancer Consensus Conference (APCCC). She contributed to the ENZAMET trial establishing enzalutamide in mHSPC, and convenes international consensus panels defining global standards for advanced prostate cancer management.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Enzalutamide in mHSPC (ENZAMET)
Contributed to the ENZAMET phase III trial establishing enzalutamide plus ADT as a survival-improving standard of care in metastatic hormone-sensitive prostate cancer, especially in the context of docetaxel combinations.
Advanced Prostate Cancer Consensus Conference
Co-founded and co-chairs the biennial APCCC, synthesizing global expert consensus on management of advanced prostate cancer to guide clinicians worldwide, producing highly cited consensus recommendations since 2017.
Representative Works 代表性著作
Enzalutamide with Standard First-Line Therapy in Metastatic Prostate Cancer (ENZAMET)
New England Journal of Medicine (2019)
Phase III trial demonstrating enzalutamide plus ADT significantly improved OS in mHSPC regardless of concurrent docetaxel use.
Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2022
European Urology (2023)
Consensus recommendations from APCCC 2022 covering treatment sequencing, biomarker use, and emerging therapies in advanced prostate cancer.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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