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Translational Medicine / 转化医学TNBC Neoadjuvant Therapy, European

Sibylle Loibl

MD, PhD

🏢German Breast Group (GBG Forschungs GmbH)🌐Germany

Chief Executive Officer and Principal Investigator

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👥Biography 个人简介

Sibylle Loibl leads the German Breast Group and has been central to multiple neoadjuvant TNBC trials including GeparSixto, GeparOcto, and BrighTNess studies. Her research has established the use of capecitabine for residual disease after neoadjuvant therapy and defined pCR as a surrogate endpoint for long-term outcomes in TNBC. She has contributed extensively to integrating PARP inhibitors and immunotherapy in neoadjuvant TNBC regimens. She is among the most productive clinical trial investigators in European breast cancer research.

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🧪Research Fields 研究领域

TNBC neoadjuvant therapy
GeparsixTo trial
capecitabine TNBC residual
olaparib neoadjuvant BRCA TNBC
pCR and prognosis TNBC

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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