Shinya Yamanaka
山中伸弥
M.D., Ph.D.
Director, Center for iPS Cell ResearchiPS细胞研究中心主任
👥Biography 个人简介
Shinya Yamanaka is a Nobel Laureate (2012) who discovered that mature cells can be reprogrammed to become pluripotent stem cells (iPSCs). This breakthrough has transformed regenerative medicine and enabled new approaches to cancer immunotherapy, including the development of iPSC-derived immune cells for off-the-shelf cellular therapies. Yamanaka's four reprogramming factors (Oct4, Sox2, Klf4, c-Myc) remain the foundation of iPSC technology.
山中伸弥是2012年诺贝尔奖获得者，他发现成熟细胞可以被重编程成为多能干细胞（iPSC）。这一突破改变了再生医学，并为癌症免疫治疗开辟了新方法，包括开发iPSC衍生的免疫细胞用于现成的细胞治疗。山中的四个重编程因子（Oct4、Sox2、Klf4、c-Myc）仍然是iPSC技术的基础。
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
iPSC Discovery
Discovered that somatic cells can be reprogrammed to pluripotency using four transcription factors.
Clinical Translation
Established CiRA to advance iPSC technology toward clinical applications including cancer therapy.
Representative Works 代表性著作
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
Cell (2006)
Discovery of iPSC reprogramming in mouse cells.
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
Cell (2007)
Generation of human iPSCs, enabling patient-specific applications.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-03-04 | All information from publicly available academic sources
Related Experts 相关专家
Carl H. June
University of Pennsylvania
Michel Sadelain
Memorial Sloan Kettering Cancer Center
Crystal L. Mackall
Stanford University
Katy Rezvani
MD Anderson Cancer Center
关注 山中伸弥 的研究动态
Follow Shinya Yamanaka's research updates
留下邮箱，当我们发布与 Shinya Yamanaka（Kyoto University / Gladstone Institutes）相关的新研究或访谈时，我们会通知你。
Explore More Experts
Discover the researchers shaping the future of cancer treatment