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Translational Medicine / 转化医学Regulatory T Cells, FOXP3 Pioneer
Shimon Sakaguchi
MD, PhD
🏢Osaka University / IFReC🌐Japan
Distinguished Professor
140
h-index
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Key Papers
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Key Contributions
👥Biography 个人简介
Shimon Sakaguchi discovered regulatory T cells in 1995 and later co-defined FOXP3 as their master transcription factor. His work transformed understanding of immune tolerance and opened Treg biology as a therapeutic target in cancer and autoimmunity. He directs the Immunology Frontier Research Center at Osaka.
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🧪Research Fields 研究领域
Treg discovery
FOXP3 lineage specification
CD25 Treg markers
autoimmunity prevention
tumor Treg
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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