Shannon Westin
香农·韦斯汀
MD, MPH
Professor and Deputy Chair, Department of Gynecologic Oncology and Reproductive Medicine妇科肿瘤及生殖医学系教授兼副主任
👥Biography 个人简介
Shannon Westin, MD, MPH is a professor and vice chair at MD Anderson specializing in endometrial cancer molecular biology, PI3K/mTOR-targeted therapies, and TCGA-based molecular subtype classification guiding treatment selection in endometrial cancer.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
PI3K/mTOR Targeted Therapy in Endometrial Cancer
Led pivotal trials evaluating PI3K, AKT, and mTOR inhibitors in endometrial cancer, defining actionable molecular targets and combination strategies to overcome resistance.
Molecular Subtype Classification and Precision Oncology
Applied TCGA molecular subtypes (POLE ultramutated, MSI-H, copy-number high/low) to guide clinical trial design and treatment selection in endometrial cancer.
Representative Works 代表性著作
PI3K pathway inhibition in endometrial cancer: biomarker analyses and clinical outcomes
Clinical Cancer Research (2020)
Defined predictive biomarkers for PI3K/mTOR inhibitor response in endometrial cancer, informing patient selection for targeted therapies.
Molecular classification of endometrial cancer: integrating TCGA subtypes into clinical practice
Gynecologic Oncology (2021)
Demonstrated clinical utility of TCGA-based molecular subtyping to predict prognosis and guide treatment in endometrial cancer patients.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
Antoni Ribas
UCLA Jonsson Comprehensive Cancer Center
Drew M. Pardoll
Johns Hopkins University
Padmanee Sharma
MD Anderson Cancer Center
Naiyer A. Rizvi
Columbia University Irving Medical Center
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