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Translational Medicine / 转化医学Smoldering Myeloma Risk Stratification, Active Myeloma Treatment

Shaji Kumar

MD

🏢Mayo Clinic🌐USA

Professor of Medicine; Chair, Hematology

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👥Biography 个人简介

Shaji Kumar is one of the world's leading myeloma clinicians and has been central to developing and validating risk stratification models for smoldering multiple myeloma, including the Mayo 2018 and 20-2-20 models that guide clinical decision-making. He led the AQUILA trial evaluating daratumumab monotherapy in high-risk SMM, demonstrating a significant reduction in progression to active myeloma. His research encompasses novel drug combinations in active myeloma, minimal residual disease endpoints, and the biology of plasma cell disorders. He is a prolific contributor to ASH and ASCO myeloma educational programs.

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🧪Research Fields 研究领域

smoldering myeloma 20-2-20 risk model
myeloma risk models Mayo 2018
active myeloma progression monitoring
daratumumab SMM AQUILA trial
myeloma plasma cell biology Mayo

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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