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Translational Medicine / 转化医学Regulatory T Cells, Fc-Optimized Anti-CTLA-4
Sergio Quezada
PhD
🏢University College London Cancer Institute🌐UK
Professor of Cancer Immunology
65
h-index
0
Key Papers
0
Key Contributions
👥Biography 个人简介
Sergio Quezada established that the antitumor activity of anti-CTLA-4 antibodies depends on Fc-mediated depletion of intratumoral regulatory T cells. His laboratory develops Fc-optimized Treg-depleting antibodies as next-generation immuno-oncology agents.
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🧪Research Fields 研究领域
Fc engineering Treg depletion
anti-CTLA-4 mechanism
intratumoral Treg
neoantigen reactive Treg
CRUK discovery
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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