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Translational Medicine / 转化医学Neural Crest Stem Cells, Melanoma, CSC Metabolism

Sean Morrison

PhD

🏢UT Southwestern Medical Center🌐USA

Director, Children's Research Institute; HHMI Investigator

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👥Biography 个人简介

Sean Morrison studies the properties of normal and cancer stem cells with emphasis on metabolic regulation of stem cell function. His laboratory discovered that melanoma cells exploit fatty acid oxidation to survive in the bloodstream during metastasis and identified antioxidant mechanisms that enable cancer stem cell survival in unfavorable environments. His work has revealed therapeutic vulnerabilities in the metabolic dependencies of cancer stem cells. He is an HHMI Investigator and has received numerous awards for contributions to stem cell biology.

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🧪Research Fields 研究领域

cancer stem cell metabolism
melanoma
neural crest stem cells
stem cell self-renewal
metastasis

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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