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Translational Medicine / 转化医学HSC Self-Renewal, Niche Signaling

Sean Morrison

PhD

🏢UT Southwestern🌐USA

Director, Children's Medical Center Research Institute

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Key Contributions

👥Biography 个人简介

Sean Morrison defined the perivascular bone marrow niche and elucidated HSC self-renewal mechanisms including SCF and CXCL12 signaling. His work is foundational to understanding how niche signals regulate normal and malignant stem cells.

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🧪Research Fields 研究领域

HSC self-renewal
bone marrow niche
SCF-kit signaling
melanoma stem cells
stem cell metabolism

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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