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Translational Medicine / 转化医学Circulating Tumor Cell Technology

Howard Scher

MD

🏢Memorial Sloan Kettering Cancer Center🌐USA

D. Wayne Calloway Chair in Urologic Oncology

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👥Biography 个人简介

Howard Scher has led pivotal clinical trials validating CTC enumeration as a prognostic and predictive biomarker in metastatic castration-resistant prostate cancer, including studies that supported FDA clearance of the CellSearch CTC system. His work demonstrating that CTC count changes during treatment predict survival has established CTCs as a clinical endpoint accepted by regulatory agencies. He leads precision medicine trials using CTC molecular profiling to guide treatment selection in advanced prostate cancer.

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🧪Research Fields 研究领域

CTC enumeration in prostate cancer
CellSearch clinical validation
CTC-based treatment decisions
Prostate cancer liquid biopsy
CTC-guided clinical trials

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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