Denis Schapiro

Denis Schapiro developed histoCAT, a widely used computational tool for analyzing spatial proteomics data from multiplexed tissue imaging, enabling systematic identification of cellular neighborhoods and spatial interaction patterns in tumors. His work on computational methods for spatial omics data has established standard analysis pipelines used across the spatial proteomics community. His tissue neighborhood identification algorithms have revealed recurring spatial motifs in the tumor microenvironment associated with distinct clinical outcomes.