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Translational Medicine / 转化医学Exosome Biomarkers, Breast Cancer

Sarah Mitchell

MD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Associate Professor of Medical Oncology

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👥Biography 个人简介

Sarah Mitchell investigates exosome-mediated drug resistance mechanisms in breast cancer and has developed EV-based biomarkers for treatment monitoring. Her research revealed that breast cancer cells shed exosomes containing HER2 fragments that can neutralize HER2-targeting antibodies. She has studied how exosomal miRNAs mediate communication between cancer cells and the tumor microenvironment. Her translational work aims to leverage exosome profiling for real-time treatment response assessment.

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🧪Research Fields 研究领域

breast cancer exosomes
circulating EVs
liquid biopsy EVs
exosome drug resistance
HER2 exosomes

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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