Learn more →
Back to Expert Scholars
Translational Medicine / 转化医学HER2-positive breast cancer

Sara Hurvitz

萨拉·胡尔维茨

MD

🏢University of Washington / Fred Hutchinson Cancer Center(华盛顿大学/弗雷德哈钦森癌症中心)🌐USA

Professor of Medicine医学教授

52
h-index
2
Key Papers
2
Awards
2
Key Contributions

👥Biography 个人简介

Sara Hurvitz is a leading expert in HER2-positive breast cancer at Fred Hutchinson Cancer Center. She has led pivotal trials of trastuzumab deruxtecan and other HER2-targeted agents, contributing to major advances in treatment algorithms for early and metastatic HER2+ breast cancer. Her research encompasses novel HER2-targeted strategies and biomarker development to optimize patient selection.

Share:

🧪Research Fields 研究领域

HER2-positive breast cancerHER2阳性乳腺癌
antibody-drug conjugates抗体药物偶联物
trastuzumab deruxtecan曲妥珠单抗德鲁替康
neoadjuvant therapy新辅助治疗
biomarker-driven treatment生物标志物驱动治疗

🎓Key Contributions 主要贡献

HER2+ Breast Cancer Drug Development

Led pivotal clinical trials of trastuzumab deruxtecan and HER2-targeted ADCs, contributing to regulatory approvals that transformed HER2+ breast cancer treatment.

Neoadjuvant HER2 Therapy

Contributed to defining optimal neoadjuvant HER2-targeted regimens and biomarker-guided approaches for treatment intensification based on residual disease.

Representative Works 代表性著作

[1]

Neoadjuvant trastuzumab, pertuzumab, and chemotherapy versus trastuzumab emtansine plus pertuzumab in HER2-positive breast cancer

Lancet Oncology (2019)

KRISTINE trial of T-DM1-based neoadjuvant therapy in HER2+ breast cancer.

[2]

Trastuzumab deruxtecan in HER2-positive metastatic breast cancer

NEJM (2020)

DESTINY-Breast01 trial establishing T-DXd efficacy in HER2+ breast cancer.

🏆Awards & Recognition 奖项与荣誉

🏆ASCO Young Investigator Award
🏆NCI Outstanding Investigator Award

📄Data Sources 数据来源

Last updated: 2026-02-01 | All information from publicly available academic sources

关注 萨拉·胡尔维茨 的研究动态

Follow Sara Hurvitz's research updates

留下邮箱,当我们发布与 Sara Hurvitz(University of Washington / Fred Hutchinson Cancer Center)相关的新研究或访谈时,我们会通知你。

我们不会泄露你的信息,也不会发送无关内容。随时可以退订。

Explore More Experts

Discover the researchers shaping the future of cancer treatment