Sara Hurvitz
萨拉·胡尔维茨
MD
Professor of Medicine医学教授
👥Biography 个人简介
Sara Hurvitz is a leading expert in HER2-positive breast cancer at Fred Hutchinson Cancer Center. She has led pivotal trials of trastuzumab deruxtecan and other HER2-targeted agents, contributing to major advances in treatment algorithms for early and metastatic HER2+ breast cancer. Her research encompasses novel HER2-targeted strategies and biomarker development to optimize patient selection.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
HER2+ Breast Cancer Drug Development
Led pivotal clinical trials of trastuzumab deruxtecan and HER2-targeted ADCs, contributing to regulatory approvals that transformed HER2+ breast cancer treatment.
Neoadjuvant HER2 Therapy
Contributed to defining optimal neoadjuvant HER2-targeted regimens and biomarker-guided approaches for treatment intensification based on residual disease.
Representative Works 代表性著作
Neoadjuvant trastuzumab, pertuzumab, and chemotherapy versus trastuzumab emtansine plus pertuzumab in HER2-positive breast cancer
Lancet Oncology (2019)
KRISTINE trial of T-DM1-based neoadjuvant therapy in HER2+ breast cancer.
Trastuzumab deruxtecan in HER2-positive metastatic breast cancer
NEJM (2020)
DESTINY-Breast01 trial establishing T-DXd efficacy in HER2+ breast cancer.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-02-01 | All information from publicly available academic sources
Related Experts 相关专家
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UCLA Jonsson Comprehensive Cancer Center
Drew M. Pardoll
Johns Hopkins University
Padmanee Sharma
MD Anderson Cancer Center
Naiyer A. Rizvi
Columbia University Irving Medical Center
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