Sant Chawla
桑特·查瓦拉
MD
Director, Sarcoma Oncology Research Center肉瘤肿瘤学研究中心主任
👥Biography 个人简介
Prolific clinical trialist and global leader in sarcoma drug development. Has led numerous phase 1–3 trials in leiomyosarcoma and other soft tissue sarcomas, including studies of TH-302 (evofosfamide) and multiple novel agents targeting sarcoma biology.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Sarcoma Clinical Drug Development
Directed a wide portfolio of sarcoma clinical trials including TH-302/evofosfamide studies targeting hypoxic tumor microenvironments in leiomyosarcoma and other STS, generating important data on hypoxia-activated prodrugs in sarcoma.
Representative Works 代表性著作
Phase III study of evofosfamide (TH-302) in combination with doxorubicin in patients with locally advanced, unresectable, or metastatic soft tissue sarcoma (TH CR-406)
Journal of Clinical Oncology (2017)
Large phase 3 sarcoma trial of evofosfamide plus doxorubicin providing critical evidence on hypoxia-targeted therapy in STS.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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