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Translational Medicine / 转化医学Trabectedin, Liposarcoma Treatment

Sant Bhatt

MD

🏢University of Texas MD Anderson Cancer Center🌐USA

Professor of Sarcoma Oncology

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Key Contributions

👥Biography 个人简介

Sant Bhatt has contributed extensively to the development and clinical evaluation of trabectedin and other cytotoxic agents in soft tissue sarcomas. His clinical research characterized the activity of trabectedin in leiomyosarcoma and myxoid liposarcoma through FUS-DDIT3 transcription factor inhibition. He has also studied mechanisms of resistance to anthracycline-based regimens in soft tissue sarcomas. His work informs current guidelines for chemotherapy selection in histology-specific sarcoma subtypes.

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🧪Research Fields 研究领域

trabectedin leiomyosarcoma
liposarcoma chemotherapy
ecteinascidin
DNA repair sarcoma
sarcoma drug development

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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