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Translational Medicine / 转化医学Hippo/YAP Pathway, Lung Cancer

Sandra Bhatt

MD, PhD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Associate Professor of Thoracic Oncology

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👥Biography 个人简介

Sandra Bhatt studies Hippo pathway biology in lung cancer and pleural mesothelioma, two tumor types with frequent Hippo pathway alterations. Her research has characterized NF2, LATS1/2, and YAP mutations in lung adenocarcinoma and mesothelioma and their functional consequences. She has demonstrated that Hippo pathway loss confers susceptibility to specific targeted therapies. Her translational work is advancing clinical strategies to exploit Hippo pathway deficiency in lung and pleural tumors.

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🧪Research Fields 研究领域

lung cancer Hippo pathway
YAP in NSCLC
NF2 mutations lung
mesothelioma YAP
Hippo lung tumor suppressor

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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