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Translational Medicine / 转化医学Epigenetic Therapy, HDAC Inhibitors

Sandra Bhatt

PhD

🏢MD Anderson Cancer Center🌐USA

Research Director, Epigenetics Program

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Key Contributions

👥Biography 个人简介

Sandra Bhatt leads the epigenetics research program at MD Anderson with expertise in HDAC inhibitors and their mechanisms of action in hematologic and solid tumors. Her research has elucidated how HDAC inhibitors induce cancer cell differentiation, apoptosis, and immune recognition. She contributed to the development and clinical evaluation of HDAC inhibitors including vorinostat and romidepsin in lymphoma and other hematologic malignancies. Her work has advanced understanding of the chromatin regulatory landscape in cancer cells.

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🧪Research Fields 研究领域

HDAC inhibitors cancer
vorinostat
romidepsin
epigenetic reprogramming
HDAC mechanism of action

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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