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Translational Medicine / 转化医学Cancer DNA Damage and Replication Stress

Leona Samson

PhD

🏢Massachusetts Institute of Technology🌐USA

Uncas and Helen Whitaker Professor of Biological Engineering

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Key Contributions

👥Biography 个人简介

Leona Samson has defined the biology of DNA alkylation damage and repair including the role of MGMT in cancer chemotherapy resistance. Her work underpins temozolomide biomarker strategy in glioblastoma. She is a founding figure in DNA repair biology.

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🧪Research Fields 研究领域

DNA alkylation damage
base excision repair
MGMT
cancer chemotherapy resistance
DNA repair biology

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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