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Translational Medicine / 转化医学RNA Modification Imaging, m6A Biology

Samie Jaffrey

MD, PhD

🏢Weill Cornell Medicine🌐USA

Greenberg-Starr Professor of Pharmacology

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Key Contributions

👥Biography 个人简介

Samie Jaffrey has developed groundbreaking tools for visualizing RNA modifications in living cells and has made fundamental discoveries about m6A function. His identification of m6Am as a cap-proximal modification regulated by FTO revealed new layers of epitranscriptomic control. His fluorescent RNA aptamer technologies (Spinach, Broccoli) have become essential tools for studying RNA dynamics in cancer cells.

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🧪Research Fields 研究领域

RNA modification imaging
m6A cap modification
RNA aptamer fluorescence
Spinach/Broccoli aptamers
translational regulation

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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