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Translational Medicine / 转化医学FcRn, Antibody Half-Life Extension
E. Sally Ward
PhD
🏢University of Southampton🌐UK
Professor of Molecular Immunology
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Key Papers
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Key Contributions
👥Biography 个人简介
Sally Ward elucidated FcRn-mediated IgG recycling and pioneered Fc engineering to extend antibody half-life, an approach now used in multiple therapeutic antibodies. Her work also enabled FcRn antagonist drugs for autoimmune disease and underpins modern Fc optimization.
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🧪Research Fields 研究领域
FcRn recycling
antibody half-life engineering
YTE mutation
Fc engineering
FcRn antagonist
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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