Sagar Lonial
萨加尔·洛尼安
MD
Chief Medical Officer & Professor of Hematology and Medical Oncology首席医疗官暨血液与肿瘤内科教授
👥Biography 个人简介
Sagar Lonial is a globally recognized myeloma authority at Emory's Winship Cancer Institute. He led pivotal trials establishing elotuzumab and daratumumab combinations as standards of care and serves as a key investigator in SWOG myeloma cooperative group studies.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Elotuzumab Development
Co-led the ELOQUENT-2 trial that established elotuzumab plus lenalidomide/dexamethasone as a standard regimen for relapsed/refractory myeloma, improving PFS in a high-risk population.
Daratumumab Combinations
Contributed to landmark trials combining daratumumab with backbone regimens, expanding first-line and relapsed myeloma treatment options across transplant-eligible and ineligible patients.
SWOG Cooperative Myeloma Research
Principal investigator and co-chair of SWOG myeloma disease committee, designing practice-changing randomized phase III trials that inform US national treatment guidelines.
Representative Works 代表性著作
Elotuzumab Therapy for Relapsed or Refractory Multiple Myeloma (ELOQUENT-2)
New England Journal of Medicine (2015)
Pivotal phase III trial demonstrating elotuzumab plus Rd improved PFS vs Rd alone in relapsed/refractory myeloma.
Daratumumab, Lenalidomide, and Dexamethasone for Multiple Myeloma (MAIA)
New England Journal of Medicine (2019)
Phase III trial showing DRd superior to Rd in transplant-ineligible newly diagnosed myeloma.
Multiple Myeloma Treatment Landscape 2026
Blood (2024)
Comprehensive review of evolving treatment paradigms incorporating novel immunotherapies in myeloma.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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