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Translational Medicine / 转化医学Interferon Signaling, CAR-T Engineering

Michel Sadelain

MD, PhD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Founding Director, Center for Cell Engineering

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👥Biography 个人简介

Michel Sadelain is a pioneer of chimeric antigen receptor (CAR) T cell engineering and founding director of the MSK Center for Cell Engineering. His laboratory has developed foundational CAR designs and studies interferon signaling responses that influence CAR-T persistence and tumor elimination. His work has defined modern CAR-T cell engineering.

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🧪Research Fields 研究领域

CAR-T cell engineering
engineered T cells
synthetic biology T cells
interferon responses in CAR-T
cell therapy

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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