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Translational Medicine / 转化医学Universal CAR-T, Off-the-Shelf Therapy

Saar Gill

MD, PhD

🏢University of Pennsylvania🌐USA

Associate Professor of Medicine

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👥Biography 个人简介

Saar Gill at the University of Pennsylvania specializes in universal allogeneic CAR-T development for off-the-shelf clinical use. He uses CRISPR gene editing to delete HLA and T cell receptor genes in donor T cells, creating universal CAR-T products that avoid graft-versus-host disease. His work on myeloid-targeting CAR-T cells for AML is particularly innovative given the target antigen challenges in this disease.

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🧪Research Fields 研究领域

universal CAR-T allogeneic
off-the-shelf CAR-T
CRISPR-edited CAR-T
myeloid CAR-T
acute myeloid leukemia

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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