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Translational Medicine / 转化医学AML Menin Inhibitor Research

Scott Armstrong

MD, PhD

🏢St. Jude Children's Research Hospital🌐USA

President and Director

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👥Biography 个人简介

Scott Armstrong is a pioneer in understanding epigenetic mechanisms driving MLL-rearranged leukemia. His laboratory discovered the critical role of DOT1L and menin in maintaining the leukemic program, providing the scientific rationale for menin inhibitor development. His work has bridged basic chromatin biology with therapeutic innovation in pediatric and adult leukemia.

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🧪Research Fields 研究领域

MLL-rearranged leukemia
Epigenetic regulation
DOT1L inhibition
Pediatric leukemia
Chromatin biology

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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