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Translational Medicine / 转化医学Lung Cancer, KRAS G12C

Ryan Corcoran

MD, PhD

🏢Massachusetts General Hospital Cancer Center🌐USA

Associate Professor of Medicine

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👥Biography 个人简介

Dr. Ryan Corcoran is a physician-scientist investigating resistance mechanisms to targeted therapies with a particular emphasis on KRAS-mutant cancers. His laboratory discovered key bypass resistance pathways to KRAS G12C inhibitors involving MET amplification and RAS pathway amplification. He also studies pan-KRAS inhibitors and KRAS G12D-targeting approaches for colorectal and pancreatic cancer.

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🧪Research Fields 研究领域

pan-KRAS inhibitors
KRAS G12C colorectal cancer
bypass resistance mechanisms
RAS multi-cancer targeting
KRAS G12D inhibitors

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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