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Translational Medicine / 转化医学Bacteriophage and Oncolytic Virus Cancer Therapy

Alasdair Russell

PhD

🏢Locus Biosciences🌐USA

Senior Director, Phage Biology

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Key Contributions

👥Biography 个人简介

Alasdair Russell leads phage biology at Locus Biosciences where he has developed CRISPR-enhanced bacteriophages (crPhage) that combine phage lytic activity with CRISPR-Cas3 genome shredding for enhanced bacterial killing. His work on scalable GMP phage manufacturing has addressed key translational barriers for clinical phage therapy in oncology. He has advanced the industrial development of engineered phage therapeutics toward regulatory approval.

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🧪Research Fields 研究领域

CRISPR-enhanced phages
crPhage technology
Phage manufacturing scale-up
GMP phage production
Phage clinical development

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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