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Translational Medicine / 转化医学Synthetic Biology and Engineered Immune Cells

Kole Roybal

PhD

🏢University of California San Francisco🌐USA

Assistant Professor of Microbiology and Immunology

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Key Contributions

👥Biography 个人简介

Kole Roybal has advanced synNotch and other synthetic receptor technologies to program custom therapeutic responses in engineered T cells for solid tumor targeting. His work demonstrates that synthetic receptors can direct T cells to produce specific therapeutic payloads only upon encountering tumor antigens. He has developed next-generation synthetic receptor platforms that expand the therapeutic logic programmable into immune cells.

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🧪Research Fields 研究领域

Synthetic Notch receptors
Custom T cell programs
Solid tumor cell therapy
Immune cell engineering
Therapeutic gene circuit design

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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