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Translational Medicine / 转化医学iPSC-Derived Cell Therapy

Derrick Rossi

PhD

🏢Moderna / Convelo Therapeutics🌐USA

Co-Founder

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👥Biography 个人简介

Derrick Rossi developed the modified mRNA-based method for generating iPSCs without genomic integration, a key advance for clinical-grade iPSC production that avoids the insertional mutagenesis risk of viral reprogramming methods. His work on synthetic mRNA technology also co-founded Moderna and has broad implications for engineering iPSC-derived cells with transient gene expression for therapeutic applications. He continues to advance non-integrating approaches to cellular reprogramming and gene modification for cell therapy.

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🧪Research Fields 研究领域

Modified mRNA reprogramming
Non-integrating iPSC generation
mRNA-based cell engineering
Stem cell technology commercialization
Cellular reprogramming methods

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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