Rolf Brekken
PhD
Professor of Surgery and Pharmacology
👥Biography 个人简介
Dr. Rolf Brekken is a vascular and tumor biology researcher at UT Southwestern who has studied platelet-derived growth factor receptor (PDGFR) signaling in tumor vasculature and stroma. He has characterized how PDGFR-mediated pericyte recruitment stabilizes blood vessels and how PDGFR inhibition in combination with VEGF blockade can impair tumor vascular support more effectively than VEGF inhibition alone. His work informs dual anti-angiogenic strategies targeting both endothelial and pericyte signaling.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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