Roland Kontermann

Roland Kontermann at the University of Stuttgart is a pioneer in bispecific antibody format engineering including BiTE molecules, diabodies, and half-life extended bispecific constructs. His research has explored the structure-function relationships of diverse bispecific formats and the pharmacokinetic implications of different molecular architectures. He has made key contributions to understanding how format affects tumor cell-to-T-cell bridging efficacy, cytokine release, and in vivo durability. His work underpins many bispecific platforms now in clinical development.