Roger Reddel
MBBS PhD FRACP FAA
Director, Children's Medical Research Institute
👥Biography 个人简介
Roger Reddel discovered the alternative lengthening of telomeres (ALT) pathway, used by approximately 10-15% of human cancers as a telomerase-independent mechanism of telomere maintenance. His work characterized ALT-associated promyelocytic leukemia bodies (APBs) as a hallmark of this pathway. He demonstrated that ALT is particularly prevalent in sarcomas, glioblastomas, and other cancer types. His research has opened new therapeutic avenues targeting ALT-positive cancers.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-03-01 | All information from publicly available academic sources
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