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Translational Medicine / 转化医学Structural Biology, Cancer Drug Design

Roger Bhatt

PhD

🏢Institute of Cancer Research, London🌐UK

Professor of Structural Chemical Biology

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Key Contributions

👥Biography 个人简介

Professor Roger Bhatt is a structural chemical biologist at the ICR who applies cryo-EM and X-ray crystallography to the structure-based design of novel cancer therapeutics. His laboratory has solved structures of key oncogenic kinases and cancer-relevant protein complexes that have guided the design of highly selective inhibitors. He integrates fragment-based screening with cryo-EM to discover allosteric binding sites on cancer driver proteins.

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🧪Research Fields 研究领域

cryo-EM cancer drug targets
protein kinase structural biology
fragment-based drug discovery
structure-based CDK inhibitor design
allosteric cancer drug mechanisms

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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