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Translational Medicine / 转化医学WNT Signaling, Cancer Biology

Roel Nusse

PhD

🏢Stanford University🌐USA

Professor of Developmental Biology

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Key Contributions

👥Biography 个人简介

Roel Nusse co-discovered the WNT1 proto-oncogene and has spent decades elucidating the WNT signaling pathway. His work established the molecular framework for understanding how WNT signals regulate cell proliferation and stem cell maintenance. He has demonstrated that aberrant WNT signaling drives numerous cancers including colorectal, breast, and liver cancers. His laboratory continues to develop therapeutic strategies targeting the WNT pathway.

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🧪Research Fields 研究领域

WNT signaling
developmental biology
cancer stem cells
beta-catenin
oncogenes

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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