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Translational Medicine / 转化医学Melanoma Stage IV Treatment, IO Resistance

Rodabe Bhatt

MD, PhD

🏢University of Michigan Rogel Cancer Center🌐USA

Clinical Assistant Professor of Medicine, Oncology

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👥Biography 个人简介

Rodabe Bhatt specializes in the treatment of advanced stage IV melanoma with a focus on overcoming resistance to checkpoint immunotherapy and targeted BRAF/MEK inhibitor therapy. Her research investigates mechanisms of immune exclusion and T cell dysfunction in melanoma that underlie primary and acquired resistance to anti-PD-1 therapy, seeking actionable targets for combination approaches. She has conducted clinical investigations of novel therapies in patients with checkpoint inhibitor-refractory advanced melanoma including LAG-3 inhibitors and adoptive T cell therapy strategies. Her translational work connects tumor microenvironment immune profiling with clinical outcomes to identify biomarkers guiding treatment selection in advanced melanoma.

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🧪Research Fields 研究领域

stage IV melanoma treatment
immunotherapy resistance melanoma
BRAF V600E targeted therapy
melanoma brain metastases
checkpoint inhibitor refractory melanoma

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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