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Translational Medicine / 转化医学RAS Oncogene, Hallmarks of Cancer

Robert Weinberg

PhD

🏢MIT / Whitehead Institute🌐USA

Professor

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Key Papers
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Key Contributions

👥Biography 个人简介

Robert Weinberg at MIT/Whitehead made foundational discoveries in cancer biology: identifying the first human oncogene (mutant RAS from a bladder cancer cell line) and the first tumor suppressor gene (RB retinoblastoma). He co-authored the landmark 'Hallmarks of Cancer' papers with Doug Hanahan that defined the conceptual framework for understanding cancer biology. His work on cancer stem cells and EMT has continued to shape cancer research.

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🧪Research Fields 研究领域

RAS oncogene discovery
RB retinoblastoma tumor suppressor
hallmarks of cancer framework
epithelial-mesenchymal transition cancer stem
cancer stem cells EMT metastasis

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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