Robert S. Langer

Robert Langer is an Institute Professor at MIT — the only active Institute Professor in the School of Engineering — and is one of the most cited engineers in history, with over 1,700 papers and 1,400 issued or pending patents. He is a co-founder of more than 40 companies including Moderna. Langer pioneered the field of controlled drug delivery, showing in 1976 that large macromolecules could be released from polymers in a controlled manner — overturning prevailing scientific dogma. This discovery launched an entirely new field and is the basis for products ranging from cancer drug-eluting stents to sustained-release pharmaceuticals. His work on lipid nanoparticles has been crucial to the mRNA vaccine revolution. He co-founded Moderna with Flagship Pioneering and his lipid nanoparticle delivery technologies are central to COVID-19 vaccines and next-generation cancer mRNA therapies. He has received virtually every major scientific prize except the Nobel Prize.

Robert Langer 是麻省理工学院的学会教授——工程学院唯一在职的学会教授——是历史上被引用次数最多的工程师之一，拥有超过1,700篇论文和1,400项已颁发或待颁发的专利。他是包括Moderna在内的40多家公司的联合创始人。 Langer 开创了控释药物递送领域，1976年证明大分子可以从聚合物中以受控方式释放——推翻了当时普遍接受的科学教条。这一发现开创了一个全新领域，是从癌症药物洗脱支架到缓释药物等产品的基础。 他在脂质纳米颗粒方面的工作对mRNA疫苗革命至关重要。他与Flagship Pioneering共同创立了Moderna，他的脂质纳米颗粒递送技术是COVID-19疫苗和下一代癌症mRNA疗法的核心。他几乎获得了除诺贝尔奖以外的所有主要科学奖项。