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Translational Medicine / 转化医学Alternative Splicing, Cancer Transcriptomics

Robert Bradley

PhD

🏢Fred Hutchinson Cancer Center🌐USA

Associate Professor, Computational Biology

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Key Contributions

👥Biography 个人简介

Robert Bradley is a leading computational biologist studying alternative splicing dysregulation in cancer, developing algorithms to detect cancer-specific splicing events from large-scale RNA-seq datasets. His laboratory has identified thousands of tumor-specific splice isoforms that generate novel protein products and potential neoantigens. He has contributed to understanding how mutations in splicing factors globally alter the cancer transcriptome. His computational tools are widely used for splicing quantification in cancer genomics studies.

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🧪Research Fields 研究领域

alternative splicing cancer
RNA processing computational biology
cancer transcriptome splicing
splicing regulatory networks cancer
RNA-seq splicing analysis

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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