Richard Fishel
PhD
Arthur G. James Comprehensive Cancer Center
👥Biography 个人简介
Richard Fishel at Ohio State made key contributions to understanding the molecular mechanism of DNA mismatch repair (MMR) — identifying the MutS homologue MSH2 and characterizing how MMR proteins recognize and correct replication errors. His work elucidating the MMR reaction mechanism and demonstrating that MMR deficiency causes microsatellite instability and Lynch syndrome has been central to understanding this cancer predisposition syndrome and to the development of immunotherapy for MMR-deficient cancers.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-03-01 | All information from publicly available academic sources
Related Experts 相关专家
Antoni Ribas
UCLA Jonsson Comprehensive Cancer Center
Drew M. Pardoll
Johns Hopkins University
Padmanee Sharma
MD Anderson Cancer Center
Naiyer A. Rizvi
Columbia University Irving Medical Center
关注 Richard Fishel 的研究动态
Follow Richard Fishel's research updates
留下邮箱，当我们发布与 Richard Fishel（Ohio State University）相关的新研究或访谈时，我们会通知你。
Explore More Experts
Discover the researchers shaping the future of cancer treatment