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Translational Medicine / 转化医学Hepatocellular Carcinoma

Richard S. Finn

理查德·芬恩

MD

🏢UCLA David Geffen School of Medicine(加州大学洛杉矶分校大卫·格芬医学院)🌐USA

Professor of Medicine, Division of Hematology/Oncology血液肿瘤内科学教授

72
h-index
2
Key Papers
3
Awards
2
Key Contributions

👥Biography 个人简介

Richard Finn is a global authority on HCC systemic therapy. He led the IMbrave150 trial establishing atezolizumab plus bevacizumab as standard first-line therapy for advanced HCC, and was central to the SHARP sorafenib trial. His work has redefined HCC treatment paradigms worldwide.

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🧪Research Fields 研究领域

Hepatocellular Carcinoma肝细胞癌
Atezolizumab-Bevacizumab阿替利珠单抗-贝伐珠单抗
IMbrave150IMbrave150研究
Sorafenib索拉非尼
Systemic Therapy系统性治疗

🎓Key Contributions 主要贡献

IMbrave150 Trial

Co-led the pivotal IMbrave150 phase III trial demonstrating superior OS and PFS for atezolizumab plus bevacizumab over sorafenib in unresectable HCC, establishing a new standard of care.

First-Line Systemic Therapy

Shaped international guidelines for HCC systemic treatment through multiple landmark trials evaluating targeted agents and immune checkpoint inhibitors in advanced disease.

Representative Works 代表性著作

[1]

Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma

New England Journal of Medicine (2020)

IMbrave150 trial demonstrating OS benefit of atezo+bev over sorafenib; practice-changing for first-line advanced HCC.

[2]

Sorafenib in Advanced Hepatocellular Carcinoma (SHARP)

New England Journal of Medicine (2008)

Landmark SHARP trial establishing sorafenib as first systemic therapy to improve survival in advanced HCC.

🏆Awards & Recognition 奖项与荣誉

🏆ASCO Outstanding Investigator Award
🏆AASLD Distinguished Service Award
🏆ESMO Fellowship

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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