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Translational Medicine / 转化医学Uveal Melanoma, Tebentafusp

Richard Carvajal

MD

🏢Columbia University Irving Medical Center🌐USA

Associate Professor

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Key Contributions

👥Biography 个人简介

Richard Carvajal at Columbia has contributed to uveal melanoma research — a rare and distinct melanoma type arising from the eye with GNAQ/GNA11 mutations (not BRAF) and high rates of liver metastases. He led clinical development of tebentafusp (a bispecific T cell receptor/anti-CD3 fusion) which demonstrated overall survival benefit in uveal melanoma — the first agent to do so in this disease — establishing a new treatment paradigm for this resistant cancer.

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🧪Research Fields 研究领域

uveal melanoma treatment
tebentafusp ImmTAC uveal melanoma
GNAQ GNA11 uveal melanoma
ocular melanoma treatment
uveal melanoma liver metastases

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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