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Translational Medicine / 转化医学Melanoma, Uveal Melanoma Tebentafusp

Richard Carvajal

MD

🏢Columbia University Irving Medical Center🌐USA

Director, Melanoma Program

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👥Biography 个人简介

Richard Carvajal is the foremost clinical researcher in uveal melanoma and led the IMCgp100-202 trial establishing tebentafusp as the first systemic therapy to show an overall survival benefit in any uveal melanoma population. His work has characterized the unique biology of GNAQ/GNA11-mutant uveal melanoma, its liver tropism, and the limited activity of conventional checkpoint inhibitors in this distinct entity.

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🧪Research Fields 研究领域

uveal melanoma tebentafusp
GNAQ GNA11 mutations uveal
metastatic uveal melanoma IO
liver-directed therapy uveal melanoma
T-cell receptor bispecific uveal

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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