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Translational Medicine / 转化医学Allogeneic Cell Therapy

Katy Rezvani

MD, PhD

🏢MD Anderson Cancer Center🌐USA

Professor of Stem Cell Transplantation

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Key Contributions

👥Biography 个人简介

Katy Rezvani is a pioneer in cord blood-derived CAR-NK cell therapy at MD Anderson Cancer Center, leading the landmark clinical trial demonstrating that off-the-shelf CAR-NK cells can achieve responses in lymphoid malignancies without causing graft-versus-host disease or significant neurotoxicity. Her work on engineering NK cells with CARs, IL-15, and suicide switches has established a new paradigm for allogeneic cell therapy that leverages the inherent safety and anti-tumor properties of NK cells. She is expanding CAR-NK approaches to solid tumors and developing iPSC-derived NK cell platforms.

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🧪Research Fields 研究领域

Cord blood-derived CAR-NK
Off-the-shelf NK cell therapy
CAR-NK clinical trials
NK cell engineering
Allogeneic innate cell therapy

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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