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Translational Medicine / 转化医学T Memory Stem Cells, Adoptive Cell Therapy

Nicholas Restifo

MD

🏢Lyell Immunopharma (formerly NCI, NIH)🌐USA

Chief Scientist, Cell Therapy

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Key Contributions

👥Biography 个人简介

Nicholas Restifo led pioneering work defining T memory stem cells (Tscm) and their superior persistence and antitumor activity after adoptive transfer. He established how early differentiated T cell subsets drive durable responses in cell therapies. He continues to advance next generation TCR and TIL approaches for solid tumors.

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🧪Research Fields 研究领域

T memory stem cells
adoptive T cell therapy
TCR therapy
tumor immunology
CD8 biology

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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