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Translational Medicine / 转化医学CAR-T Clinical Development, B Cell Malignancies

Renier Brentjens

MD, PhD

🏢Roswell Park Comprehensive Cancer Center🌐USA

Chair, Department of Medicine

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Key Contributions

👥Biography 个人简介

Renier Brentjens was one of the first investigators to conduct CAR-T clinical trials, demonstrating durable remissions in B cell ALL and CLL patients. He has contributed extensively to understanding cytokine release syndrome and CAR-T safety management. His clinical and translational work has informed the development of commercial CAR-T products used globally today.

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🧪Research Fields 研究领域

CAR-T clinical trials
ALL CAR-T therapy
safety CAR-T
tumor antigen targeting
cytokine release syndrome

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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