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Translational Medicine / 转化医学Global Oncology Milestone 2026

Rengaswamy Sankaranarayanan

仁卡斯瓦米·桑卡拉纳拉亚南

MD

🏢HERO (Health, Early Detection, Research & Oncology) / International Agency for Research on Cancer (IARC, emeritus)(HERO研究机构/国际癌症研究机构(荣休))🌐India

Distinguished Senior Scientist; Former Head, Screening Group, IARC; Founder, IARC Screening Hub杰出高级科学家;IARC筛查组前负责人;IARC筛查中心创始人

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

The scientist most responsible for evidence that visual inspection with acetic acid (VIA) and single-visit HPV testing can realistically eliminate cervical cancer in low-resource settings. His IARC-led cluster randomized trials in India involving over 200,000 women produced the foundational RCT evidence that underpins every major global cervical cancer screening guideline and the WHO elimination strategy.

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🧪Research Fields 研究领域

Cervical Cancer Screening宫颈癌筛查
Oral Cancer Screening口腔癌筛查
Cancer Early Detection in LMIC中低收入国家癌症早期检测
HPV TestingHPV检测
Cancer Prevention India印度癌症预防

🎓Key Contributions 主要贡献

VIA and Single-Visit Cervical Cancer Screening RCTs

Led cluster-randomized trials in India involving 225,000 women demonstrating that VIA screen-and-treat approach reduced cervical cancer mortality by 31% over 12 years in a real-world LMIC setting, producing the landmark evidence that enabled WHO to recommend VIA as a primary screening option for countries without cytology or HPV infrastructure.

Oral Cancer Screening Mortality Reduction

Conducted a 15-year cluster RCT in Kerala, India — the world's only oral cancer screening mortality RCT — demonstrating that community health worker-delivered oral visual inspection reduced oral cancer mortality by 43% in tobacco users, establishing the evidence base for WHO and India's national oral cancer control programs.

Representative Works 代表性著作

[1]

Effect of visual screening on cervical cancer incidence and mortality in Tamil Nadu, India: a cluster-randomised trial

The Lancet (2007)

Definitive cluster-RCT demonstrating that VIA screening with immediate cryotherapy in a single visit reduced cervical cancer incidence and mortality in a low-resource South Indian population, reshaping global screening guidelines.

🏆Awards & Recognition 奖项与荣誉

🏆IARC Scientific Achievement Award
🏆Indian Council of Medical Research Lifetime Achievement Award
🏆Union for International Cancer Control (UICC) Cancer Control Award
🏆Padma Shri (Government of India)

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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