Rein Willemze
莱因·威勒姆泽
MD, PhD
Emeritus Professor of Dermatology; Former Head, Cutaneous Lymphoma and Skin Tumour Unit皮肤科荣誉退休教授;前皮肤淋巴瘤和皮肤肿瘤科主任
👥Biography 个人简介
Rein Willemze is Emeritus Professor of Dermatology at Leiden University Medical Center and one of the world's foremost authorities on rare cutaneous malignancies including Kaposi sarcoma and primary cutaneous lymphomas. He played a foundational role in the WHO-EORTC classification of primary cutaneous lymphomas and the WHO Classification of Skin Tumours. His work on Kaposi sarcoma elucidated HHV-8 pathogenesis in different epidemiological variants and informed treatment algorithms for classic, endemic, iatrogenic, and epidemic KS. His contributions have shaped how rare skin cancers are classified and managed globally.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
WHO Classification of Skin Tumours
Senior editor and contributor to the WHO Classification of Skin Tumours (Blue Book), defining pathological criteria and clinical entities for Kaposi sarcoma, adnexal tumours, and rare mesenchymal skin malignancies.
Kaposi Sarcoma Pathogenesis and Treatment
Contributed key clinicopathological studies on HHV-8 viral mechanisms in different KS subtypes and established management frameworks distinguishing localised from systemic KS requiring liposomal anthracycline or paclitaxel chemotherapy.
Representative Works 代表性著作
WHO-EORTC classification of primary cutaneous lymphomas and rare skin tumours: 2023 update
Blood (2023)
Authoritative classification update incorporating new molecular data on Kaposi sarcoma subtypes, sebaceous carcinoma, and other rare adnexal malignancies.
Kaposi sarcoma: clinical variants, HHV-8 biology, and treatment paradigms
European Journal of Cancer (2021)
Comprehensive review of Kaposi sarcoma epidemiology, HHV-8 pathogenesis across classic, endemic, iatrogenic and epidemic variants, and evidence-based treatment selection.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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