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Translational Medicine / 转化医学skin cancer

Rein Willemze

莱因·威勒姆泽

MD, PhD

🏢Leiden University Medical Center(莱顿大学医学中心)🌐Netherlands

Emeritus Professor of Dermatology; Former Head, Cutaneous Lymphoma and Skin Tumour Unit皮肤科荣誉退休教授;前皮肤淋巴瘤和皮肤肿瘤科主任

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Rein Willemze is Emeritus Professor of Dermatology at Leiden University Medical Center and one of the world's foremost authorities on rare cutaneous malignancies including Kaposi sarcoma and primary cutaneous lymphomas. He played a foundational role in the WHO-EORTC classification of primary cutaneous lymphomas and the WHO Classification of Skin Tumours. His work on Kaposi sarcoma elucidated HHV-8 pathogenesis in different epidemiological variants and informed treatment algorithms for classic, endemic, iatrogenic, and epidemic KS. His contributions have shaped how rare skin cancers are classified and managed globally.

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🧪Research Fields 研究领域

Kaposi Sarcoma卡波西肉瘤
HHV-8 BiologyHHV-8生物学
Cutaneous Lymphoma皮肤淋巴瘤
Rare Skin Malignancies罕见皮肤恶性肿瘤
WHO Classification Skin TumoursWHO皮肤肿瘤分类

🎓Key Contributions 主要贡献

WHO Classification of Skin Tumours

Senior editor and contributor to the WHO Classification of Skin Tumours (Blue Book), defining pathological criteria and clinical entities for Kaposi sarcoma, adnexal tumours, and rare mesenchymal skin malignancies.

Kaposi Sarcoma Pathogenesis and Treatment

Contributed key clinicopathological studies on HHV-8 viral mechanisms in different KS subtypes and established management frameworks distinguishing localised from systemic KS requiring liposomal anthracycline or paclitaxel chemotherapy.

Representative Works 代表性著作

[1]

WHO-EORTC classification of primary cutaneous lymphomas and rare skin tumours: 2023 update

Blood (2023)

Authoritative classification update incorporating new molecular data on Kaposi sarcoma subtypes, sebaceous carcinoma, and other rare adnexal malignancies.

[2]

Kaposi sarcoma: clinical variants, HHV-8 biology, and treatment paradigms

European Journal of Cancer (2021)

Comprehensive review of Kaposi sarcoma epidemiology, HHV-8 pathogenesis across classic, endemic, iatrogenic and epidemic variants, and evidence-based treatment selection.

🏆Awards & Recognition 奖项与荣誉

🏆European Academy of Dermatology and Venereology Lifetime Achievement Award
🏆International Society for Cutaneous Lymphomas Founder's Award
🏆Dutch Dermatology Society Honorary Medal

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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