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Translational Medicine / 转化医学In Situ Vaccination and Intratumoral Therapy

David Reardon

MD

🏢Dana-Farber Cancer Institute🌐USA

Clinical Director, Center for Neuro-Oncology

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Key Contributions

👥Biography 个人简介

David Reardon has advanced intratumoral immunotherapy approaches for glioblastoma including convection-enhanced delivery of immune agonists and oncolytic viruses directly into brain tumors. His clinical trials have explored in situ vaccination strategies adapted for the unique immune environment of the central nervous system. He has demonstrated the feasibility and potential of intratumoral immune activation for notoriously immunotherapy-resistant brain cancers.

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🧪Research Fields 研究领域

Glioblastoma intratumoral therapy
Brain tumor in situ vaccination
Convection-enhanced delivery
Neuro-oncology immunotherapy
CNS intratumoral approaches

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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