Razelle Kurzrock
拉泽尔·库尔兹罗克
MD
Professor of Medicine; Director, Clinical Trials Program; Molecular Tumor Board Pioneer内科学教授；临床试验项目主任；分子肿瘤委员会先驱
👥Biography 个人简介
Razelle Kurzrock, MD is a global leader in personalized oncology and innovative clinical trial design. She pioneered the PREDICT trial and molecular tumor board concept, advocating for N-of-1 precision trial approaches. Her work underpins the evolution of individualized cancer therapy across solid tumors.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Molecular Tumor Board and Personalized Oncology
Pioneered the institutional molecular tumor board model and individualized genomic-guided therapy, demonstrating improved outcomes when treatment is matched to patients' specific molecular alterations.
PREDICT Trial and N-of-1 Designs
Developed PREDICT and related personalized trial frameworks evaluating biomarker-matched therapies in refractory cancers, establishing proof-of-concept for individualized oncology treatment paradigms.
Representative Works 代表性著作
Molecular Profiling and Targeted Therapy for Advanced Solid Tumors: A Prospective Study (PREDICT)
Journal of Clinical Oncology (2019)
Prospective study demonstrating clinical benefit of genomic-matched targeted therapy guided by molecular tumor board in heavily pretreated solid tumor patients.
Efficacy in a Genomically Characterized Population of Refractory Solid Tumors
Nature Medicine (2021)
Demonstrates clinical benefit of precision therapy guided by comprehensive molecular profiling and multidisciplinary tumor board across diverse refractory cancers.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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Drew M. Pardoll
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Naiyer A. Rizvi
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