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Translational Medicine / 转化医学Cancer Trials, Dose Escalation Design

Mark J. Ratain

MD

🏢University of Chicago🌐USA

Leon O. Jacobson Professor of Medicine

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Key Contributions

👥Biography 个人简介

Mark Ratain is a leading voice in cancer drug dose optimization and pharmacology-guided development. He has advocated for rational dose selection and post-marketing dose reevaluation of many approved oncology agents. His work directly informed the FDA Project Optimus initiative.

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🧪Research Fields 研究领域

pharmacology
dose optimization
clinical pharmacogenomics
interventional oncology
drug development

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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